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IV Therapy

NAD+

High-dose NAD+ infusion to fuel cellular energy, DNA repair and longevity pathways.

2–4 hours
Physician-supervised

Overview

Nicotinamide adenine dinucleotide (NAD+) is a coenzyme central to mitochondrial energy production, DNA repair, and sirtuin activity. Levels decline sharply with age; direct IV repletion has become a cornerstone of longevity medicine.

Key benefits

  • Supports mitochondrial function and ATP output
  • Activates sirtuins and PARP-mediated DNA repair
  • Enhances mental clarity, focus and mood
  • Aids recovery from alcohol, jet lag and burnout
  • Complements peptide and hormone protocols

How it works

NAD+ is infused slowly over 2–4 hours to minimize the characteristic chest tightness and flushing associated with rapid delivery. Dosing is titrated per patient (250–1000 mg per session).

Mechanism

NAD+ donates electrons in the mitochondrial electron transport chain, drives sirtuin (SIRT1–7) deacetylation, and enables PARP-mediated DNA repair — pathways strongly implicated in aging biology.

Who is this for

  • Adults 35+ optimizing healthspan
  • Patients addressing cognitive fog or fatigue
  • Individuals in addiction or burnout recovery
  • Athletes and biohackers stacking with peptides

Considerations & safety

Infusion speed matters: rapid delivery causes transient chest pressure, nausea or flushing. Slow titration eliminates most side effects. Not recommended in active cancer without oncologist coordination.

This page is educational and not medical advice. All VitaFlow protocols require evaluation by a licensed Florida physician.

Frequently asked

Why does the infusion take so long?+

Slower infusion prevents the discomfort NAD+ can cause when pushed too fast.

How many sessions do I need?+

Most protocols start with a loading series of 4–10 infusions, then monthly maintenance.

Can I combine NAD+ with peptides?+

Yes — many longevity patients pair NAD+ with peptides like Epithalon or CJC-1295.

Are oral or nasal alternatives as good?+

Oral precursors help but do not replicate the plasma levels of IV NAD+.

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Ready to feel your best?

Meet with a VitaFlow physician to design a protocol tailored to your goals, biomarkers, and lifestyle.