IV Therapy

NAD+ IV Therapy: Process, Duration and What to Consider

7 min read

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme involved in mitochondrial energy production, DNA repair and sirtuin signalling. Levels decline with age, which is why NAD+ infusions have become a fixture of longevity medicine.

This guide explains what happens during an NAD+ IV session at our Miami Beach clinic, how long it takes, what patients commonly feel, and the screening we require before treatment.

What NAD+ IV therapy is

NAD+ is delivered intravenously so it bypasses digestion and reaches the bloodstream directly. Oral precursors such as NR and NMN can raise NAD+ metabolites, but they do not reproduce the plasma levels achieved by an infusion.

At VitaFlow we typically infuse 250–500 mg per session, titrated to the individual after a clinician reviews history, medications and goals.

The process, step by step

Consultation and screening first: medical history, current medications, and labs where indicated. NAD+ is not appropriate for everyone, and a clinician makes that call.

On the day, a nurse places the IV and starts the drip slowly. You are seated in a private treatment area; most patients read, work or rest.

A clinician monitors you throughout and adjusts the infusion rate based on how you feel. Aftercare guidance and follow-up timing are provided before you leave.

Why it takes two to four hours

NAD+ pushed too quickly commonly causes chest tightness, flushing, nausea or abdominal cramping. Slowing the rate largely prevents this, which is why sessions are long compared with a standard vitamin drip.

Plan for two to four hours depending on dose and tolerance. Bring headphones, a laptop or a book, and eat beforehand.

Who it may suit — and who should wait

Patients often ask about NAD+ for energy, mental clarity, recovery and healthy-aging support. Evidence in humans is still developing, so we describe NAD+ as something that may support these areas rather than something that treats or reverses disease.

Pregnancy, breastfeeding, active infection, certain cardiac conditions and some medications warrant deferral or an alternative protocol. Screening exists precisely to catch this.

Cost, frequency and whether a shorter IM or oral protocol makes more sense are all part of the consultation. Every VitaFlowFL protocol starts with a physician-led consultation, comprehensive labs, and a written plan — so care is personalized, monitored, and safe.

Frequently asked questions

+How long does an NAD+ IV take?

Usually two to four hours. The infusion is deliberately slow because faster delivery commonly causes chest tightness and flushing.

+How will I feel during the infusion?

Most patients feel warmth or mild pressure in the chest if the rate is too fast; slowing the drip resolves it. Tell your nurse and the rate is adjusted.

+How often would I have NAD+ therapy?

Frequency is individual. Some patients start with a short series and then space sessions out; your clinician sets a schedule based on your response and goals.

+Is NAD+ available as mobile IV therapy?

Ask during your consultation. Because of the length and monitoring involved, NAD+ is generally best delivered in-clinic in Miami Beach.

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Talk to a VitaFlowFL physician.

Every protocol at VitaFlowFL starts with labs, symptoms and a written plan — reviewed by a Florida-licensed doctor. Book a 15-minute consult to see if it fits.

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